Calamine lotion is a skin protectant. It works by soothing and protecting the skin following minor skin irritations.
It works by its counter-irritant effect. After application to the skin the calamine evaporates, which produces a cooling effect that helps distract from the itch. This sensation also helps relieve sunburn.
Calamine lotions and creams also contain the active ingredient zinc oxide, which has antiseptic properties that help prevent infection from scratching.
Warning: Calamine lotion is for external use on the skin only.
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